Plasma or serum from patients with systemic sclerosis alters behaviour of normal erythrocytes.

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Plasma endothelin-1 levels in patients with systemic sclerosis: influence of pulmonary or systemic arterial hypertension.

OBJECTIVES To investigate the behaviour of circulating endothelin-1 (ET-1) in patients affected by systemic sclerosis and to elucidate the relationship between systemic and pulmonary plasma peptide and arterial pressure levels. METHODS Plasma ET-1 concentrations were determined in 48 patients affected by systemic sclerosis (41 women, seven men; mean age 47.2 (SD 5.5) years) with or without sy...

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Malondialdehyde and nitric oxide levels in erythrocytes from patients with systemic sclerosis.

OBJECTIVE To investigate malondialdehyde (MDA) and nitric oxide (NO) levels in the erythrocytes from patients with systemic sclerosis (SSc). SUBJECTS AND METHODS Twenty-nine patients diagnosed as having SSc and 16 volunteer healthy subjects (as control group) participated in the study. Fasting blood samples were obtained from the patients and healthy subjects in anticoagulated tubes (with EDT...

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Decreased serum IL-7 levels in patients with systemic sclerosis.

Sirs, Interleukin-7 (IL-7) was originally defined as a pre-B lymphocyte growth factor and was subsequently found to augment the growth of T lymphocytes. A recent study showed that IL-7 is an anti-fibrogenic factor in pulmonary fibrosis in vitro. In this study, we determined the serum levels of IL-7 in patients with SSc. Forty-three patients with SSc and 28 healthy controls were included in the ...

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Plasma paraoxonase activity in patients with systemic sclerosis.

BACKGROUND & OBJECTIVE Systemic sclerosis (SSc) is a connective tissue disease characterized vascular damage and fibrosis. The aim of this study was to investigate the possible relation between systemic sclerosis and paraoxonase which is an antioxidant enzyme on the HDL. METHODS Twenty nine patients with SSc and 16 healthy subjects (control group) participated in the study. Plasma cholesterol...

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Plasma D-dimer concentration in patients with systemic sclerosis

BACKGROUND Systemic sclerosis (SSc) is an autoimmune disorder of the connective tissue characterized by widespread vascular lesions and fibrosis. Little is known so far on the activation of the hemostatic and fibrinolytic systems in SSc, and most preliminary evidences are discordant. METHODS To verify whether SSc patients might display a prothrombotic condition, plasma D-dimer was assessed in...

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ژورنال

عنوان ژورنال: Annals of the Rheumatic Diseases

سال: 1985

ISSN: 0003-4967

DOI: 10.1136/ard.44.6.395